CMC Manager - Antibody Drug Conjugates

CMC Manager - Antibody Drug Conjugates (ADCs) Cambridge, UK Hybrid

Are you a scientist with a passion for revolutionising cancer treatment? Do you have expertise in bioconjugation and a track record of driving ADCs into the clinic? If so, this role could be a great fit for you.

CSG is excited to partner with a rapidly growing pharmaceutical company that is shaping the future of antibody-drug conjugates (ADCs). As their CMC Manager, you will be at the forefront of innovation, leading ADC programs through the IND/CTA process to bring life-changing therapies to patients.

Your Impact

In this dynamic role, you will:

• Spearhead the progression of ADCs through the IND/CTA process and into clinical trials.
• Collaborate closely with research and discovery teams to advance early-stage ADC programs.
• Select and manage third-party CDMOs for ADC development and manufacturing.
• Provide scientific and strategic guidance to internal teams and external CDMO partners.
• Lead the authoring of Module 3 IND applications with regulatory precision.
• Offer expertise in conjugation technologies, linkers, payload selection, and ADC formulation.
• Drive innovation by advising on emerging ADC technologies and industry advancements.
• Serve as the go-to ADC expert within the company for regulatory and analytical requirements.

What You Bring

To thrive in this role, you'll need:

• A PhD in a relevant life sciences field.
• Extensive hands-on experience in ADC development, including diverse conjugation techniques.
• A proven track record in leading and authoring module 3 of IND submissions
• A passion for optimising processes and deep knowledge of cutting-edge ADC technologies.\
• Experience in CDMO selection and management for ADC development.
• Strong understanding of quality and regulatory standards for advancing ADCs into the clinic
• Exceptional scientific problem-solving and strategic decision-making skills.

Why Join?

• This is more than just a job-it's an opportunity to be a key driver of change in oncology treatments. You'll work alongside leading experts in a collaborative and forward-thinking environment, where your contributions will directly shape the future of cancer treatment.
• Relocation & Visa support is available for candidates eager to join this exciting journey in the UK.